HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Joshua A Sommers Selected Research

Mitochondrial DNA (mtDNA)

7/2016Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
10/2014DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Joshua A Sommers Research Topics

Disease

14Genomic Instability
01/2022 - 10/2002
12Neoplasms (Cancer)
10/2020 - 07/2005
8Werner Syndrome (Werner's Syndrome)
10/2016 - 06/2003
8Fanconi Anemia (Fanconi's Anemia)
04/2015 - 11/2010
7Bloom Syndrome
04/2015 - 03/2004
5Premature Aging
10/2016 - 08/2004
5Breast Neoplasms (Breast Cancer)
11/2015 - 07/2005
4Chromosomal Instability (Chromosome Stability)
11/2021 - 09/2013
4Inborn Genetic Diseases (Disease, Hereditary)
07/2016 - 07/2005
2Cockayne Syndrome (Syndrome, Cockayne)
04/2015 - 09/2013
2Chromosome Breakage
07/2014 - 01/2013
2Xeroderma Pigmentosum (Kaposi's Disease)
01/2014 - 09/2013
2Carcinogenesis
07/2009 - 01/2006
1Ichthyosis (Xeroderma)
01/2022
1Microsatellite Instability
10/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2018
1Mitochondrial Diseases (Mitochondrial Disease)
07/2016
1Renal Cell Carcinoma (Grawitz Tumor)
10/2014
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
10/2013
1Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita)
09/2013
1Ataxia Telangiectasia (Louis Bar Syndrome)
09/2013
1Chromosome Aberrations (Chromosome Abnormalities)
09/2013
1Bone Marrow Failure Disorders
09/2013
1Microcephaly
01/2013
1Rothmund-Thomson Syndrome (Syndrome, Rothmund-Thomson)
07/2005

Drug/Important Bio-Agent (IBA)

20DNA (Deoxyribonucleic Acid)IBA
01/2020 - 10/2002
12Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2003
10DNA HelicasesIBA
01/2022 - 08/2004
6RecQ HelicasesIBA
11/2015 - 03/2004
4A-Form DNA (A-DNA)IBA
01/2020 - 10/2002
4Mitomycin (Mitomycin-C)FDA LinkGeneric
07/2014 - 01/2013
4Exonucleases (3' 5' Exonuclease)IBA
07/2010 - 10/2002
3EnzymesIBA
10/2016 - 01/2005
3Flap EndonucleasesIBA
01/2005 - 10/2002
2Mitochondrial DNA (mtDNA)IBA
07/2016 - 10/2014
2DNA-Binding Proteins (DNA Binding Protein)IBA
07/2014 - 08/2005
2Replication Protein AIBA
07/2014 - 08/2005
2NSC 617145IBA
10/2013 - 09/2013
2IronIBA
09/2013 - 01/2013
2SulfurIBA
09/2013 - 01/2013
21,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
09/2013 - 01/2006
2Werner Syndrome HelicaseIBA
09/2013 - 01/2011
2Bloom syndrome proteinIBA
02/2011 - 03/2004
1ZincIBA
01/2022
1ChromatinIBA
11/2021
1Biomarkers (Surrogate Marker)IBA
10/2020
1RNA (Ribonucleic Acid)IBA
04/2015
1UbiquitinIBA
04/2015
1Ligases (Synthetase)IBA
04/2015
1Pharmaceutical PreparationsIBA
10/2013
1DNA-Activated Protein KinaseIBA
09/2013
1maleimideIBA
01/2011
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2011
11-(propoxymethyl)maleimideIBA
01/2011
1telomestatinIBA
01/2011
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2011
1Staphylococcal Protein A (Protein A)IBA
03/2004
1EndonucleasesIBA
03/2004
1human EXO1 proteinIBA
06/2003

Therapy/Procedure

1Drug Therapy (Chemotherapy)
10/2013